Interleukin-10 (IL-10) 1082 promoter Polymorphisms and plasma IL-10 levels in patients with bacterial sepsis
نویسندگان
چکیده
منابع مشابه
The frequency of interleukin-10 (IL-10) polymorphisms in patients with peptic ulcer and chronic gastritis
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متن کاملthe frequency of interleukin-10 (il-10) polymorphisms in patients with peptic ulcer and chronic gastritis
abstract introduction: peptic ulcer is a common problem in medicine with serious impacts on the quality of life of patients. it has been shown that helicobacter pylori infection is related with inflammatory responses of gastric mucosa. however, some patients remain asymptomatic. sustained colonization and chronic inflammation increase the risk of gastritis and peptic ulcer. the aim of this stud...
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Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 A/C, -819 C/T, -1082 A/G), IL-6 (-174 C/G) and IL-17 (-197 G/A) in Iranian women. Method: Po...
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The induced production of proinflammatory and anti-inflammatory cytokines is considered important for the development of sepsis and its sequelae. Polymorphisms in the IL-10 gene promoter could influence its expression and sepsis susceptibility. Results obtained by Dr Ling and colleagues demonstrated that the -1082A allele was significantly associated with lower lipopolysaccharide-induced IL-10 ...
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Background: As a chronic inflammatory condition, psoriasis results from an interaction between genetic and immunologic factors in a predisposing environment. In spite of compelling evidence for the role of T cells and cytokines in psoriasis, interleukin (IL)- 10 and IL-22 have not been sufficiently investigated. Objective: To assess the serum levels of IL-10 and IL-22 in patients with psori...
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ژورنال
عنوان ژورنال: Romanian Journal of Internal Medicine
سال: 2020
ISSN: 2501-062X
DOI: 10.2478/rjim-2020-0033